高雪
个人简介
姓名：高雪 科研团队：营养与安全
邮箱：huaxue_gaoxue@126.com 政治面貌：中共党员
职称：副教授 入职时间：2013.7
高雪，博士，渤海大学副教授，硕士生导师。主要从事食品质量安全检测领域的相关研究工作，发表SCI论文30余篇，授权专利1件，主持承担国家自然科学基金1项，主持辽宁省食品安全重点实验室项目1项，渤海大学博士科研启动基金项目1项，渤海大学海洋研究院项目1项。
教育背景
1. 2008.09-2013.06：吉林大学，分析化学，理学博士
2. 2004.09-2008.06：辽宁师范大学，化学（师范），学士
工作经历
1. 2016.11-至 今：渤海大学, 食品科学与工程学院, 副教授
2. 2015.02-2016.11：渤海大学, 食品科学与工程学院, 讲师
3. 2013.07-2015.02：渤海大学, 化学化工与食品安全学院, 讲师
学术论文
1. Xiao Jingyi, Li Tongtong, Sun Jianing, Gao Xue*, Target-inhibited MCOF-Apt@Ag self-assembly for multi-modal biosensor for detecting Vibrio parahaemolyticus. Biosensors and Bioelectronics, 2026, 294, 118248 (SCI一区; IF=10.5)
2. Liu Menglong, Chen Litao, Li Jinyang, Gao Jiayan, Gao Xue*, A biosensor based on Mn, Ce doped carbon dots with oxidase-like activity for multi-mode detection of ofloxacin. Sensors and Actuators: B. Chemical, 2025, 445, 138606 (SCI一区; IF=8.0)
3. Liu Yiyao, Liu Menglong, Xiao Jingyi, Ren Yi, Li Jinyang, Gao Jiayan, Chen Litao, Gao Xue*, A ratiometric fluorescence biosensor based on enzyme-cascade signal amplification technology for the detection of lincomycin. Food Control, 2025, 175, 111344 (SCI一区; IF=6.303)
4. Liu Menglong, Liu Yiyao, Xiao Jingyi, Ren Yi, Gao Xue*, Colorimetric-ratiometric fluorescence sensors dual-mode detection of ofloxacin based on Fe-Ni bimetallic metal-organic frameworks and carbon dots. Food Control, 2025, 169, 110989 (SCI一区; IF=6.652)
5. Xiao Jingyi, Ren Yi, Liu Menglong, Liu Yiyao, Chen Litao, Gao Jiayan, Li Jinyang, Gao Xue*, Ultrasensitive detection of Vibrio parahaemolyticus based on boric acid-functionalized Eu (III)-based metal–organic framework, Analytica Chimica Acta, 2025, 1344, 343682 (SCI二区; IF=5.7)
6. Jia Mu, Xiao Jingyi, Liu Menglong, Ren Yi, Liu Yiyao, Gao Xue*, Colorimetry/fluorescence dual-mode detection of gentamicin based on curcumin nanoparticles and manganese dioxide nanosheets. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2025, 341, 126419 (SCI二区; IF=4.3)
7. Zhang Hongmei, Liu Menglong, Liu Yiyao, Xiao Jingyi, Ren Yi, Gao Xue*, Portable real-time determination of Escherichia coli O157:H7 and Staphylococcus aureus based on smartphones and hydrogels, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2025, 325, 125119 (SCI二区; IF=4.3)
8. Gao Xue, Zhang Hongmei, Liu Lu, Jia Mu, Li Xuepeng*, Li Jianrong*, Nano-biosensor based on manganese dioxide nanosheets and carbon dots for dual-mode determination of Staphylococcus aureus. Food Chemistry, 2024, 432, 137144 (SCI一区; IF=8.5)
9. Gao Xue, Jia Mu, Zhang Hongmei, Liu Lu, Li Xuepeng*, Li Jianrong*, A smartphone‑assisted portable dual‑mode immunoassay of gentamicin based on curcumin nanoparticles and carbon dots. Microchimica Acta, 2024, 191, 515-526 (SCI二区; IF=6.408)
10. Gao Xue, Liu Lu, Jia Mu, Zhang Hongmei, Li Xuepeng*, Li Jianrong *, A dual-mode fluorometric/colorimetric sensor for sulfadimethoxine detection based on Prussian blue nanoparticles and carbon dots, Microchimica Acta, 2024, 191, 284-297 (SCI二区; IF=6.408)
11. Liu Menglong, Wang Ying, Xiao Jingyi, Liu Yiyao, Ren Yi, Gao Xue*, Colorimetric immunoassay of furazolidone metabolites based on iron‑copper bimetallic organic framework nanoenzyme. Microchimica Acta, 2024, 191, 575-585 (SCI二区; IF=6.408)
12. Liu Menglong, Liu Yiyao, Xiao Jingyi, Ren Yi, Gao Xue*, Ratiometric fluorescence aptasensor based on structure-switching-triggered mimetic enzyme activity for sensitive detection of enrofloxacin. Chemical Physics Letters, 2024, 857, 141684 (SCI四区; IF=2.8)
13. Gao Xue, Ma Zhiying, Liu Xiuying, Zhong Keli, Tang lijun, Li Xuepeng*, Li Jianrong*, A highly sensitive ratiometric fluorescent sensor for copper ions and cadmium ions in scallops based on nitrogen doped graphene quantum dots cooperating with gold nanoclusters. Food Chemistry. 2022, 369, 130964 (SCI一区; IF=8.5)
14. Gao Xue, Sun Minjun, Liu Xiuying, Li Xuepeng, Li Jianrong*, A ratiometric fluorescence platform based on carbon dots for visual and rapid detection of copper(II) and fluoroquinolones. Microchimica Acta. 2022, 189, 144 (SCI二区; IF=6.408)
15. Gao Xue, Sun Mingjun, Liu Xiuying, Zhong Keli, Tang lijun, Li Jianrong*, A fluorescent and colorimetric dual-recognition probe based on copper(II)-decorated carbon dots for detection of phosphate. Analytical Methods, 2021, 13, 5003–5010 (SCI三区; IF=2.7)
16. Gao Xue, Song Yu, Zhang Qiang, Liu Xiuying, Tang lijun, Li Jianrong*, Application of maleimide modified graphene quantum dots and porphyrin fluorescence resonance energy transfer in the design of“turn-on”fluorescence sensors for biothiols. Analytica Chimica Acta, 2020, 1108, 46-53 (SCI二区; IF=5.7)
17. 贾穆, 高雪*, 张红梅, 刘璐, 贾穆, 励建荣, 姜黄素纳米传感器在食品快速检测中的应用, 中国食品学报, 2025, 25, 463-478.
18. 张红梅, 高雪*, 刘璐, 贾穆, 励建荣*, 纳米生物传感器在食源性致病菌检测中的应用研究进展, 食品科学, 2024, 45, 348-357.
19. 孙敏君, 高雪*, 徐阳鑫, 刘秀英, 励建荣*, 食品中氟喹诺酮类药物残留的快速检测研究进展. 食品科学, 2022, 43, 383-391.
20. 徐阳鑫, 高雪*, 孙敏君, 刘秀英, 励建荣, 粘菌素功能化的Fe3O4-GQDs 作为荧光探针用于快速检测大肠杆菌. 食品工业科技, 2021, 42(11), 9-14.
代表性专利
1. 高雪; 孙敏君; 张强; 励建荣; 张德福; 刘秀英. 用于检测恩诺沙星的基于结构转换的比率荧光适配体传感器及其应用. CN202210786742.6.
承担教学
本科生《有机化学》；研究生《现代仪器分析技术》
研究生招生专业
每年招收食品营养专业硕士研究生1-2名。